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IoT for Real-Time Measurement of High-Throughput Liquid Dispensing in Laboratory Environments

Published:

March 4, 2020

Author:

Justin Shumate, Pierre Baillargeon, Timothy P. Spicer, and Louis Scampavia

Abstract:

Critical to maintaining quality control in high-throughput screening is the need for constant monitoring of liquid-dispensing fidelity. Traditional methods involve operator intervention with gravimetric analysis to monitor the gross accuracy of full plate dispenses, visual verification of contents, or dedicated weigh stations on screening platforms that introduce potential bottlenecks and increase the plate-processing cycle time.

We present a unique solution using open-source hardware, software, and 3D printing to automate dispenser accuracy determination by providing real-time dispense weight measurements via a network-connected precision balance. This system uses an Arduino microcontroller to connect a precision balance to a local network. By integrating the precision balance as an Internet of Things (IoT) device, it gains the ability to provide real-time gravimetric summaries of dispensing, generate timely alerts when problems are detected, and capture historical dispensing data for future analysis. All collected data can then be accessed via a web interface for reviewing alerts and dispensing information in real time or remotely for timely intervention of dispense errors. The development of this system also leveraged 3D printing to rapidly prototype sensor brackets, mounting solutions, and component enclosures....

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Company Information:

SLAS Technology

SLAS Technology is a peer-reviewed scientific journal published by the Society for Laboratory Automation and Screening in partnership with SAGE Publications

Thousand Oaks, California, USA

Publication or Online Resource

  • Phone +1 805 499 9774

SLAS Technology website

Company Postings:

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