I suppose it depends on your layout software. My weak recollection of what PowerPCB does is allow you to set up rules as far as spacing and where parts are placed, then you run the rule check, er something like that.
As far as "Also what I"m thinking of doing is makeing an excel spreadsheet to generate a DFM score for assemblies. Does anyone else do this?", I know I think about it all the time. At my last job we had a PCB design review team that assessed manufacturability upon the first build of any new layout (proto or any significant design change) and submitted findings/recommendations to design. Some fly, some don't. We didn't get to the "score sheet" level, but the idea was discussed. At this job, very few of our customers are motivated to make changes for dfm's sake.
Another company I worked for did keep score for new product design (an ME was assigned to the design team) and it did include PCB layout, but that was when things were simpler (large pth boards with no or very limited SMT) and they did their own pcb assembly.
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