It all dependes on the de-paneling method.
V-score - .100" is probably to thick for manual seperation. There are machines that I believe can cut through a V-Score up to .125" or greater
Breakaway tabs - .100" is getting to the limit when doing this manually. However there are "nibblers" that take care of a thick board for depaneling.
PCB router - no problem.
If using the breakaways, you need to make sure that there is no circuitry within .100" of tabs. These will sometimes cause a little damage at the break area. V-Score seperation also requires a "keepout" distance that is dependent on the type and model of machine used.
So the answer is yes you can panelize a .100" board. the other question is Can your assembly house get it apart?
Russ
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